59587-09-6

  • Product Name:N-Acetyl-L-cysteine Ethyl Ester (NACET)
  • Molecular Formula:C7H13NO3S
  • Purity:99%
  • Molecular Weight:191.251
Inquiry

Product Details

Melting Point:44.1-44.5 °C

Purity:99%

Quality Factory Supply 99% Pure N-Acetyl-L-cysteine Ethyl Ester (NACET) 59587-09-6 with Efficient Delivery

  • Molecular Formula:C7H13NO3S
  • Molecular Weight:191.251
  • Vapor Pressure:0.000104mmHg at 25°C 
  • Melting Point:44.1-44.5 °C 
  • Refractive Index:1.48 
  • Boiling Point:337.6 °C at 760 mmHg 
  • PKA:9.17±0.10(Predicted) 
  • Flash Point:158 °C 
  • PSA:97.69000 
  • Density:1.138 g/cm3 
  • LogP:0.82430 

N-Acetyl-L-cysteine ethyl ester(Cas 59587-09-6) Usage

InChI:InChI=1/C7H13NO3S/c1-3-11-7(10)6(4-12)8-5(2)9/h6,12H,3-4H2,1-2H3,(H,8,9)/t6-/m0/s1

59587-09-6 Relevant articles

Preclinical Characterization of 3β-(N-Acetyl l -cysteine methyl ester)-2aβ,3-dihydrogaliellalactone (GPA512), a Prodrug of a Direct STAT3 Inhibitor for the Treatment of Prostate Cancer

Escobar, Zilma,Bjartell, Anders,Canesin, Giacomo,Evans-Axelsson, Susan,Sterner, Olov,Hellsten, Rebecka,Johansson, Martin H.

, p. 4551 - 4562 (2016)

The transcription factor STAT3 is a pote...

Superior properties of N-acetylcysteine ethyl ester over n-acetyl cysteine to prevent retinal pigment epithelial cells oxidative damage

Tosi, Gian Marco,Giustarini, Daniela,Franci, Lorenzo,Minetti, Alberto,Imperatore, Francesco,Caldi, Elena,Fiorenzani, Paolo,Aloisi, Anna Maria,Sparatore, Anna,Rossi, Ranieri,Chiariello, Mario,Orlandini, Maurizio,Galvagni, Federico

, p. 1 - 12 (2021)

Oxidative stress plays a key role in the...

COMPOUNDS AND IMPLANTS FOR TREATING OCULAR DISORDERS

-

Paragraph 0215, (2021/05/15)

The present disclosure relates to therap...

Synthesis of the 4-aza cyclopentenone analogue of Δ12,14-15-deoxy-PGJ2 and S-cysteine adducts

Conway, Lorna,Riccio, Anna,Santoro, M. Gabriella,Evans, Paul

supporting information, (2020/05/18)

The synthesis of a series of 4-aza cross...

Protection of human retinal pigment epithelial cells from oxidative damage using cysteine prodrugs

Bulumulla, Chandima,Catchpole, Timothy,Christie, Abigail,Csaky, Karl G.,Kularatne, Ruvanthi N.,Stefan, Mihaela C.,Takacs, Alison

, p. 386 - 394 (2020/04/17)

Age-related macular degeneration (AMD) i...

59587-09-6 Process route

ethanol
64-17-5

ethanol

N-acetylcystein
616-91-1,7696-05-1

N-acetylcystein

(R)-2-acetylamino-3-mercapto-propionic acid ethyl ester
59587-09-6

(R)-2-acetylamino-3-mercapto-propionic acid ethyl ester

Conditions
Conditions Yield
With thionyl chloride; at 0 - 20 ℃; for 4h; Inert atmosphere;
47%
With thionyl chloride; at 20 ℃; for 3.5h;
47%
With thionyl chloride; at 30 ℃; for 3h;
46%
With thionyl chloride; at 0 - 20 ℃; Inert atmosphere;
With sulfuric acid; at 90 ℃; for 24h;
650 mg
With thionyl chloride; at -5 ℃;
With oxalyl dichloride; at 0 - 20 ℃;
C<sub>26</sub>H<sub>27</sub>NO<sub>3</sub>S
1032314-56-9

C26H27NO3S

(R)-2-acetylamino-3-mercapto-propionic acid ethyl ester
59587-09-6

(R)-2-acetylamino-3-mercapto-propionic acid ethyl ester

Conditions
Conditions Yield
With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

59587-09-6 Upstream products

  • 24037-21-6
    24037-21-6

    N,N'-diacetyl-L-cystine diethyl ester

  • 84310-90-7
    84310-90-7

    (R)-2-Amino-3-(1,5-diacetoxy-3-methoxy-2-methyl-9-oxo-9H-xanthen-4-yldisulfanyl)-propionic acid ethyl ester

  • 64-17-5
    64-17-5

    ethanol

  • 616-91-1
    616-91-1

    N-acetylcystein

59587-09-6 Downstream products

  • 1039118-73-4
    1039118-73-4

    C16H27NO4S

  • 1040363-82-3
    1040363-82-3

    (1R,2R)-2-(1'-hydroxy-1'-methyl-ethyl)-1-cyclohexanol

Relevant Products