475-83-2
- Product Name：Nuciferine
- Molecular Formula：C19H21NO2
- Purity：99%
- Molecular Weight：295.381
Product Details
Melting Point:165.5°C
Purity:99%
Nuciferine Good Supplier In Bulk Supply High Purity 475-83-2
- Molecular Formula:C19H21NO2
- Molecular Weight:295.381
- Vapor Pressure:1.27E-07mmHg at 25°C
- Melting Point:165.5°C
- Refractive Index:1.596
- Boiling Point:430.7 °C at 760 mmHg
- PKA:7.87±0.20(Predicted)
- Flash Point:151.9 °C
- PSA：21.70000
- Density:1.15 g/cm3
- LogP:3.39380
NUCIFERINE(Cas 475-83-2) Usage
|
Safety Profile |
Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx. |
InChI:InChI=1/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3
475-83-2 Relevant articles
Stereoselective total synthesis of (S)- and (R)-nuciferine using benzyne chemistry
Casagrande, Gleison A.,Deflon, Victor M.,Martins, Gabriel R.,Oliveira-Silva, Diogo,Perecim, Givago P.,Pinto, Leandro M. C.,Raminelli, Cristiano
, (2020/08/13)
Total syntheses of (S)- and (R)-nuciferi...
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells
Nakamura, Seikou,Nakashima, Souichi,Tanabe, Genzo,Oda, Yoshimi,Yokota, Nami,Fujimoto, Katsuyoshi,Matsumoto, Takahiro,Sakuma, Rika,Ohta, Tomoe,Ogawa, Keiko,Nishida, Shino,Miki, Hisako,Matsuda, Hisashi,Muraoka, Osamu,Yoshikawa, Masayuki
, p. 779 - 787 (2013/02/25)
Methanolic extracts from the flower buds...
Aporphine alkaloid synthesis and diversification via direct arylation
Lafrance, Marc,Blaquiere, Nicole,Fagnou, Keith
, p. 811 - 825 (2008/02/12)
Palladium-catalyzed direct arylation of ...
475-83-2 Process route
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
![(6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline](/upload/2024/8/bfb0ee6f-a98f-4008-bf38-45f760429ced.png)
-
4846-19-9,20454-22-2,37659-74-8,54750-04-8
(6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
-
-
475-83-2,5868-18-8,16654-38-9,37659-75-9
R-(-)-nuciferine
| Conditions | Yield |
|---|---|
|
formaldehyd; (6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline;
In
methanol; water;
at 20 ℃;
for 0.5h;
With
sodium tetrahydroborate;
In
methanol; water;
at 20 ℃;
|
84% |
-
![(R)-1,2-dimethoxy-4,5,6a,7-tetrahydrodibenzo[de,g]quinoline-6-carboxylic acid methyl ester](/upload/2024/8/949ffc42-17d8-4811-bdbf-291f54e02b0c.png)
-
(R)-1,2-dimethoxy-4,5,6a,7-tetrahydrodibenzo[de,g]quinoline-6-carboxylic acid methyl ester
-
-
475-83-2,5868-18-8,16654-38-9,37659-75-9
R-(-)-nuciferine
| Conditions | Yield |
|---|---|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 24h;
|
88% |
475-83-2 Upstream products
-
186581-53-3
diazomethane
-
6545-25-1
(-)-N-methylasimilobine
-
18107-18-1
diazomethyl-trimethyl-silane
-
120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine
475-83-2 Downstream products
-
5531-98-6
atherosperminine
-
3175-79-9
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1,2-diol
-
7630-74-2
dehydronuciferine
-
4846-19-9
(6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
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