5266-20-6
- Product Name：Lithium orotate
- Molecular Formula：C5H3LiN2O4
- Purity：99%
- Molecular Weight：162.031
Product Details
Melting Point:300oC
Purity:99%
Buy Good Quality Lithium orotate 5266-20-6 with a minimum purity of 99%
- Molecular Formula:C5H3LiN2O4
- Molecular Weight:162.031
- Melting Point:300oC
- PSA：115.60000
- LogP:-1.81300
Lithium orotate(Cas 5266-20-6) Usage
| Description | Lithium orotate is a salt of orotic acid and lithium. |
|
Purification Methods |
The salt is soluble in H2O at 17o and 100o. Best to acidify an aqueous solution of the salt, isolate the free acid (see above) which is recrystallised from H2O (as monohydrate) m 345-347o (345-346o), then dissolve it in EtOH, add an equivalent amount of LiOH in EtOH and evaporate. Its solubility in H2O is 1.28% (17o) and 2.34% (100o). [Bachstez Chem Ber 63 1000 1930, Johnson & Shroeder J Am Chem Soc 54 2941 1932, UV: Shugar & Fox Biochim Biophys Acta 9 199 1952, Beilstein 25 III/IV 1759.] |
| Uses | Lithium orotate gets inside of neurons, affecting their inner workings in ways that can greatly benefit mood. It supports the brain's natural detoxification process and promotes the natural balance of brain neurotransmitters. Even in microdoses, lithium orotate can help calm brain activity and promote mood stability. |
InChI:InChI=1/C5H4N2O4.Li.H2O/c8-3-1-2(4(9)10)6-5(11)7-3;;/h1H,(H,9,10)(H2,6,7,8,11);;1H2/q;+1;/p-1
5266-20-6 Relevant articles
A combined NMR crystallographic and PXRD investigation of the structure-directing role of water molecules in orotic acid and its lithium and magnesium salts
P?ppler, Ann-Christin,Walker, David,Brown, Steven P.
, p. 224 - 236 (2017/01/16)
Despite the abundance of hydrates, their...
Different pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania
Anthony G. Pacholko , Lane K. Bekar
, Journal of Psychiatric Research Volume 164 , August 2023, Pages 192-201
Intriguingly, lithium orotate (LiOr) is suggested to possess unique uptake characteristics that would allow for reduced dosing and mitigation of toxicity concerns. We hypothesized that due to differences in pharmacokinetics, LiOr is more potent with reduced adverse effects.
5266-20-6 Upstream products
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65-86-1
orotic acid
5266-20-6 Downstream products
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65-86-1
2,4-dihydroxypyrimidine-6-carboxylic acid
-
26830-94-4
2,4-dichloropyrimidine-6-carboxylic acid chloride
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