506-37-6

  • Product Name:Nervonic Acid
  • Molecular Formula:C24H46 O2
  • Purity:99%
  • Molecular Weight:366.628
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Product Details

Melting Point:42 - 44 C

Appearance:clear to yellowish crystalline powder

Purity:99%

Factory Sells Best Quality Nervonic Acid 506-37-6 with USP

  • Molecular Formula:C24H46 O2
  • Molecular Weight:366.628
  • Appearance/Colour:clear to yellowish crystalline powder 
  • Vapor Pressure:1.68E-10mmHg at 25°C 
  • Melting Point:42 - 44 C  
  • Refractive Index:1.4806 (estimate) 
  • Boiling Point:479.2ºC 
  • PKA:4.78±0.10(Predicted) 
  • Flash Point:>110 ºC 
  • PSA:37.30000 
  • Density:0.887g/cm3 
  • LogP:8.44910 

Nervonic acid(Cas 506-37-6) Usage

Biochem/physiol Actions

Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.

Source

Sources of Nervonic acid include oil crop seeds, oil-producing microalgae and other microorganisms. Transgenic technology can also be used to improve the source and production of Nervonic acid.

Definition

ChEBI: Nervonic Acid is a monounsaturated fatty acid with a 24-carbon backbone and the sole double bond originating from the 9th carbon from the methyl end, with this bond in the cis- configuration. It is a metabolite found in the aging mouse brain.

General Description

Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc.

Uses Nervonic acid benefits the treatment of neurological diseases and the health of brain.

InChI:InChI=1/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-

506-37-6 Relevant articles

A Facile and Efficient Method for the Synthesis of Labeled and Unlabeled Very Long Chain Polyunsaturated Fatty Acids

Hamberg, Mats

, p. 489 - 494 (2021/04/19)

Several methods are available for elonga...

High-level production of nervonic acid in the oleaginous yeast Yarrowia lipolytica by systematic metabolic engineering

Hang Su, Penghui Shi, Zhaoshuang Shen, Huimin Meng, Ziyue Meng, Xingfeng Han, Yanna Chen, Weiming Fan, Yun Fa, Chunyu Yang, Fuli Li & Shi’an Wang

Communications Biology volume 6, Article number: 1125 (2023)

For example, the KCS ACJ61777.1 (GenBank No. EU871787) identified in the biennial grass Lunaria annua used C22:1-acyl-CoA as substrate to synthesize nervonic acid when expressed in the Ethiopia mustard Brassica carinata34, while it elongated C18:1-acyl-CoA to produce mainly eicosenoic acid (C20:1, ω-9) and erucic acid (C22:1, ω-9, EA) when expressed in the yeast Rhodosporidium toruloides...

506-37-6 Process route

1-hydroxy-cis-15-tetracosene
50995-29-4

1-hydroxy-cis-15-tetracosene

Nervonic acid
506-37-6

Nervonic acid

Conditions
Conditions Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In water; acetonitrile; at 20 ℃; for 7h;
70%
methyl cis-tetracos-15-enate
2733-88-2

methyl cis-tetracos-15-enate

Nervonic acid
506-37-6

Nervonic acid

Conditions
Conditions Yield
With sodium hydroxide; In ethanol; at 60 ℃; for 1h; Inert atmosphere;
 

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