A Comprehensive Analysis of PQQ

01/22/2025 16:22:31

With the continuous deepening of research, modern science has a deeper understanding of "aging". PQQ, an antioxidant that exists in almost all our foods, is considered to have the function of "prolonging life" and "protecting the brain" and has attracted much attention. Some businesses have also begun to promote its effects more exaggeratedly, such as "Xueba Pills", "Brain Age Reduction Factors", "Eat 2 pills a day to get a high-end face", etc., which makes people wonder if PQQ is really as magical as the rumors? Scientific research shows that PQQ does help improve cognitive function and sleep, help relieve inflammation and assist in cardiovascular protection.

So, what is PQQ? This article will scientifically interpret this nutrient that the industry has high hopes for from the definition, source, mechanism of action, function and other aspects of PQQ.
What is PQQ?
It is a redox cofactor and antioxidant that is essential for human health. Current studies have shown that there are a large number of enzymes in organisms that require PQQ as a cofactor. Therefore, PQQ plays an important role in the growth and development of all organisms.
Since its discovery in 1979, PQQ has been known for its excellent antioxidant capacity. In fact, PQQ's association with cognitive function, sleep, body inflammation and cardiovascular, as well as its need for external intake, has led to heated discussions about whether PQQ will become the "next nutritional superstar". PQQ comes directly from soil or soil bacteria and exists in all organisms, including bacteria, plants, and animals. Studies have confirmed that common intestinal bacteria in the human body cannot produce PQQ, and dietary intake is the main source of PQQ in the human body. The content of free PQQ in food ranges from 1-30ng/g. The following are some foods with high PQQ content:
Characteristics of PQQ
(I)Strong antioxidant properties The strong antioxidant properties of PQQ are reflected in that it can catalyze repeated redox reactions to a large extent. Its strong antioxidant properties can fight against destructive molecules that damage cells, thereby preventing damage to heart, brain, and skin cells.

Under the same environment and conditions, PQQ can undergo 20,000 catalytic transformations, while vitamin C can only undergo 
(II) Promote nerve cell growth Researchers have found that PQQ can help strengthen nerve cells in the body when treating cognitive impairment and some dementia. In an environment containing PQQ, the peak value of nerve cell synthesis that is beneficial to neuron development can increase by 40 times.
(III) Catalyze mitochondrial growth As a cofactor, PQQ can participate in the mitochondrial regeneration process in aging cells, increase the activity of related enzymes, stimulate mitochondrial growth, and thus increase the energy level of organs.
Effects of PQQ
(I) Promote cognitive function Relevant data from multiple studies have shown that PQQ can promote the growth of nerve cells and help improve human cognitive impairment.
(II) Improve sleep and relieve fatigue In clinical trials, researchers found that PQQ helps improve sleep quality and relieve fatigue to a certain extent. Researchers believe that PQQ's improvement in sleep quality and relief of fatigue may be due to its strong antioxidant properties and its role in promoting the growth of mitochondria.
(III) Relieve inflammation In a crossover experiment in which 10 subjects took a fruit-flavored drink containing PQQ (the dosage of PQQ in the experiment was 0.3 mg/kg per day), the consumption of PQQ significantly reduced multiple inflammatory indicators. (IV) Protect cardiovascular system PQQ's strong antioxidant properties and its ability to promote mitochondrial regeneration can help improve the vitality of myocardial cells and protect the heart and cardiovascular system.