The secret of youth! How many of the top ten effects of NAD+ do you know?
10/29/2025 11:35:22
What is NAD+?
NAD is one of the most important coenzymes in the human body, also called coenzyme 1, and its full name is nicotinamide adenine dinucleotide (nicotinamide dinucleotide). It is a key substance discovered in the field of human aging inhibition.
Dr. David, winner of the Bell Prize in Medicine, conducted an NAD+ test on mice. A week later, he found that the mice equivalent to 70 years old in humans had returned to their youthful state at the age of 20! After research, it was found that NMN can increase the level of NAD+ in the human body, and NAD+ will gradually decrease with age, thus revealing the secret of aging!
Professor David Sinclair of Harvard Medical School found that NAD+ has a good anti-aging effect. Subsequently, many academic papers on NAD+ were published in authoritative academic journals represented by "Cell", "Nature" and "Science".
Top ten effects of NAD+
Let's take a look at what effects modern science has discovered about NAD+.
1 Anti-aging
NAD+ maintains chemical communication between the cell nucleus and mitochondria. Weakened communication is an important cause of cell aging.
NAD+ can remove the increasing number of erroneous DNA codes during cell metabolism, maintain normal gene expression, maintain normal cell function, and slow down the aging of human cells.
2 Repair DNA damage
NAD+ is a necessary substrate for the DNA repair enzyme PARP, and has a significant impact on DNA repair, gene expression, cell development, cell survival, chromosome reconstruction and gene stability.
3 Activate longevity proteins Sirtuins are often called the longevity protein family, which plays an important regulatory role in cell functions, such as inflammation, cell growth, circadian rhythm, energy metabolism, neuronal function, and stress resistance, and NAD+ is an important enzyme for synthesizing longevity proteins.
Activate all 7 longevity proteins in the human body, which plays an important role in cell resistance, energy metabolism, preventing cell mutation, apoptosis and aging.
4 Provide energy
catalysis to produce more than 95% of the energy required for life activities. Mitochondria in human cells are the power plants of cells. NAD+ is an important coenzyme for generating energy molecules ATP in mitochondria, converting nutrients into energy required by the human body.
5 Promote vascular
regeneration and maintain vascular elasticity Blood vessels are indispensable tissues for life activities. As we age, blood vessels gradually lose their flexibility, become harder, thicker, and narrower, causing "atherosclerosis".
NAD+ can increase the activity of elastin in blood vessels, thereby maintaining the elasticity of blood vessels and maintaining the health of blood vessels.
6 Promote metabolism
Metabolism is the sum of various chemical reactions in the body. The body will continuously exchange substances and energy. When this exchange stops, the life of the body will end.
Professor Anthony of the University of California and his research team found that NAD+ can effectively improve the slowdown of cell metabolism associated with aging, thereby improving people's physical health and prolonging life.
7 Protect heart health
The heart is the most important organ of the human body, and the level of NAD+ in the body plays a vital role in maintaining the normal functioning of the heart.
The reduction of NAD+ may be related to the occurrence mechanism of many cardiovascular diseases, and a large number of basic studies have also confirmed the role of supplementing NAD+ on heart disease.
8 Prevent cardiovascular and cerebrovascular diseases
Studies have shown that almost all seven subtypes of sirtuins (SIRT1-SIRT7) are related to the occurrence of cardiovascular diseases. Sirtuins are considered to be an exciting target for the treatment of cardiovascular diseases, especially SIRT1.
NAD+ is the only substrate of Sirtuins. Timely supplementation of NAD+ for the human body can fully activate the activity of various subtypes of Sirtuins, thereby protecting cardiovascular health and preventing cardiovascular diseases.
9 Promote hair growth
The main reason for promoting hair growth and hair loss is the loss of vitality of hair matrix cells, and the loss of vitality of hair matrix cells is because the level of NAD+ in the human body decreases. Hair matrix cells do not have enough ATP to synthesize hair proteins, thus losing vitality and causing hair loss.
Therefore, supplementing NAD+ can strengthen the tri-anion cycle and produce ATP, so that hair matrix cells have enough ability to produce hair proteins, thereby improving hair loss.
10 Weight management
Overweight not only affects people's quality of life and physical condition, but also induces other chronic diseases. Studies have shown that NAD+ precursor NMN can reduce the weight of overweight patients.
In 2017, Professor David Sinclair of Harvard Medical School and a team from an Australian medical school conducted a comparative experiment on obese female mice, comparing treadmill exercise for 9 weeks with daily NMN administration for 18 days. The study found that the effect of NMN on liver fat metabolism and synthesis was significantly greater than exercise.
